Tree Parity Machine Rekeying Architectures

The necessity to secure the communication between hardware components in embedded systems becomes increasingly important with regard to the secrecy of data and particularly its commercial use. We suggest a low-cost (i.e. small logic-area) solution for flexible security levels and short key lifetimes. The basis is an approach for symmetric key exchange using the synchronisation of Tree Parity Machines. Fast successive key generation enables a key exchange within a few milliseconds, given realistic communication channels with a limited bandwidth. For demonstration we evaluate characteristics of a standard-cell ASIC design realisation as IP-core in 0.18-micrometer CMOS-technology

Hydrogen-fueled internal combustion engines

The threat posed by climate change and the striving for security of energy supply are issues high on the political agenda these days. Governments are putting strate-gic plans in motion to decrease primary energy use, take carbon out of fuels and facilitate modal shifts. Taking a prominent place in these strategic plans is hydrogen as a future en-ergy carrier. A number of manufacturers are now leasing demonstration vehi-cles to consumers using hydrogen-fueled internal combustion engines (H2ICEs) as well as fuel cell vehicles. Developing countries in particular are pushing for H2ICEs (powering two- and three-wheelers as well as passenger cars and buses) to decrease local pollution at an affordable cost. This article offers a comprehensive overview of H2ICEs. Topics that are dis-cussed include fundamentals of the combustion of hydrogen, details on the differ-ent mixture formation strategies and their emissions characteristics, measures to convert existing vehicles, dedicated hydrogen engine features, a state of the art on increasing power output and efficiency while controlling emissions and modeling

Electricity powering combustion: hydrogen engines

Hydrogen is ameans to chemically store energy. It can be used to buffer energy in a society increasingly relying on renewable but intermittent energy or as an energy vector for sustainable transportation. It is also attractive for its potential to power vehicles with (near-) zero tailpipe emissions. The use of hydrogen as an energy carrier for transport applications is mostly associated with fuel cells. However, hydrogen can also be used in an internal combustion engine (ICE). When converted to or designed for hydrogen operation, an ICE can attain high power output, high efficiency and ultra low emissions. Also, because of the possibility of bi-fuel operation, the hydrogen engine can act as an accelerator for building up a hydrogen infrastructure. The properties of hydrogen are quite different from the presently used hydrocarbon fuels, which is reflected in the design and operation of a hydrogen fueled ICE (H2ICE). These characteristics also result in more flexibility in engine control strategies and thus more routes for engine optimization. This article describes the most characteristic features of H2ICEs, the current state of H2ICE research and demonstration, and the future prospects

A Key Establishment IP-Core for Ubiquitous Computing

A most critical and complex issue with regard to constrained devices in the ubiquitous and pervasive computing setting is secure key exchange. The restrictions motivate the investigation and discussion of alternative solutions. We suggest a low hardware-complexity solution for authenticated symmetric key exchange, using a Tree Parity Machine Rekeying Architecture. An authenticated key exchange is formulated from within the tree parity machine interaction concept and requires only few transmissions. It averts a Man-In-The-Middle attack and the currently known attacks on the non-numbertheoretic on principle. A key exchange can be performed within a few milliseconds, given typical limited bandwidth wireless communication channels. A flexible rekeying functionality enables the exploitation of the achievable key exchange rates. Characteristics of a standard-cell ASIC design realization as IP-core in 0.18 micron CMOS-technology are evaluated

Setting a best practice for determining the EGR rate in hydrogen internal combustion engines

Exhaust gas recirculation (EGR) is an effective way to reduce NOx-emissions and increase the efficiency of hydrogen fueled internal combustion engines. Knowledge of the exact amount of EGR is crucial to understand the effects of EGR. As the exhaust gas flow is pulsating and chemically aggressive, the flow rate is typically not measured directly and has to be derived from other quantities. For hydrocarbon fuels, the EGR rate is generally calculated from a molar CO2 balance, but for hydrogen engines this obviously cannot be used as there are no CO2 emissions, and consequently no standard practice has been established. This work considers three methods to calculate the amount of EGR in a hydrogen engine. The first one is based upon a volume balance in the mixing section of exhaust gases and fresh air. The second and third method uses a molar balance of O-2 and H2O respectively in this mixing section. The three methods are developed and tested for their accuracy with an error analysis. Additionally, the methods are applied to an experimental dataset gathered on a single cylinder hydrogen engine. Both the theoretical analysis and the experimental results confirm the method based on an O-2 molar balance as the most accurate one. The least practical method is the one based on an H2O balance as it requires additional relative humidity sensors and is less accurate than the others

A Three-Hybrid Approach to Scanning the Proteome for Targets of Small Molecule Kinase Inhibitors

AbstractIn this study, we explored the application of a yeast three-hybrid (Y3H)-based compound/protein display system to scanning the proteome for targets of kinase inhibitors. Various known cyclin-dependent kinase (CDK) inhibitors, including purine and indenopyrazole analogs, were displayed in the form of methotrexate-based hybrid ligands and deployed in cDNA library or yeast cell array-based screening formats. For all inhibitors, known cell cycle CDKs as well as novel candidate CDK-like and/or CDK-unrelated kinase targets could be identified, many of which were independently confirmed using secondary enzyme assays and affinity chromatography. The Y3H system described here may prove generally useful in the discovery of candidate drug targets

Unterstützung kommunalplanerischer Prozesse mit CityGLM-basierter Anbindung Modelica-getriebener Quartierssimulationen

Eine integrale Planung städtischer (Energie-)Systeme bedarf einer planungsbegleitenden Unterstützung durch IT-basierte Planungs- und Simulationswerkzeuge. Die durchgängige Anwendung dieser digitalen Planungshilfsmittel wird allerdings bislang insbesondere durch den sehr hohen Aufwand bei der Spezifizierung und Erfassung benötigter Datengrundlagen sowie eine mangelhafte Interoperabilität zwischen den Systemen gehemmt. Im Rahmen eines Forschungsverbundprojektes wird dieses Problemfeld mittels praxisbezogener Prozessanalysen genauer spezifiziert und die technische und fachliche Integration durch die prozessbezogene Spezifikation relevanter Informationsbedarfe sowie die Entwicklung einer darauf aufbauenden, bidirektionalen Schnittstelle auf Basis des etablierten virtuellen Stadtmodellstandards CityGML verbessert. Als exemplarisches Anwendungsszenario innerhalb kommunaler Planungsprozesse wurde die Ausweisung von Vorranggebieten der Fernwärmenutzung basierend auf einer räumlichen Analyse des Wärmebedarfs für verschiedene Entwicklungsszenarien mittels einer bidirektionalen standard-basierten Koppelung von CityGML und Modelica ausgearbeitet

MEDELLER: homology-based coordinate generation for membrane proteins

Motivation: Membrane proteins (MPs) are important drug targets but knowledge of their exact structure is limited to relatively few examples. Existing homology-based structure prediction methods are designed for globular, water-soluble proteins. However, we are now beginning to have enough MP structures to justify the development of a homology-based approach specifically for them